Question

The Colts pulled out another one against the Texans last night. They're 22-3 all-time against Houston. What are the only other two NFL series in which the teams have played at least 20 times and one team has won over 80 percent of the games? With both series, the teams have never been in the same division.

Answer

Denver, which is 22-5 all-time against Cleveland. That includes a 3-0 mark in playoff games.